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TITLE:

COMPARISON OF HAEMOGRAM PARAMETERS OF PATIENTS WITH THYROID PAPILLARY CANCER

AUTHORS:

Dr Sabreena Hafeez, Dr Hafsa Butter, Dr Hira Zarqoon Javed

ABSTRACT:

Introduction: Papillary thyroid cancer (PTC) is the most epidemic type of thyroid cancers, accounting for approximately 80% of all diagnosed thyroid cancers. Objectives: The main objective of the study is to compare the haemogram parameters of patients with thyroid papillary cancer. Material and methods: This descriptive study was conducted in Gujranwala Medical College, Gujranwala during March 2019 to December 2019. Data related to PTC patients and those with nodular hyperplasia (NH). Age, gender, thyroid stimulating hormone (TSH) levels were noted. PTC patients were graded according to the tumour nodule metastasis (TNM) stages of the American Joint Committee on Cancer (AJCC) and only those with stage 1 were included as the number of patients graded to have other stages were insufficient and they were excluded. Results: The data was collected from 141 patients. Thyroglobulin levels of 23(43%) PTC patients ranged 0.04- 0.54ng/ml and 34(64%) received postoperative RAI. In 23(43.3%) PTC cases, tumour diameter was <1cm (range: 0.1-0.9cm) and in 30(56.7%) cases, the diameter was 1cm (range: 1-7cm). Nodule diameters of NH cases ranged 0.4- 7.5cm, and the diameters of PTC patients were significantly lower than NH patients (p: 0.001. In PTC patients, tumour localisation, tumour focus, lymph node metastasis and vascular invasion were noted. Conclusion: It is concluded that platelet indices, except PLR, cannot assist in distinguishing benign goiter from thyroid cancer.

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