::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

METABOLIC SYNDROME IN PATIENTS OF ACUTE CORONARY SYNDROME

AUTHORS:

Dr Zainab Ali, Dr Haider Ali, Dr Umer Rasul

ABSTRACT:

Introduction: Metabolic syndrome, also referred to as insulin resistance syndrome, is a cluster of risk factors in an individual that may precede type 2 diabetes mellitus. It is also associated with an increased risk of cardiovascular disease. Objectives: The main objective of the study is to analyse the metabolic syndrome in patients of acute coronary syndrome. Material and methods: This cross-sectional study was conducted in SIMS, Lahore during June 2019 to December 2019. Clinical histories from inpatients with ACS admitted to coronary or intensive care units in hospital were selected for this study. Demographic and clinical data were obtained from the clinical histories. Results: The total prevalence of MS using ATPIII criteria was 50.9% (292 patients). We found no MS components in 29 patients (5.1%), 1 in 96 (16.7%), 2 in 157 (27.4%), 3 in 135 (23.5%), 4 in 115 (20%), and all 5 in 42 (7.3%) patients. The most frequent component of MS was carbohydrate metabolism disorder, followed by reduced HDLc levels, hypertension, hyper triglyceridemia and, in last place, obesity. In total, 85.3% had carbohydrate metabolism disorder and the same percentage had low HDLc levels; 80.5% had hypertension, 65.4% had hypertriglyceridemia, and 51.7% had a BMI above the established cutoff point. Conclusion: It is concluded that women with ACS show a higher prevalence and a greater number of components of MS than men.