::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

A CROSS SECTIONAL STUDY ON THE SPECTRUM OF DIFFERENT CAUSES OF CHRONIC COUGH AND CORRELATION OF THESE CAUSES WITH BASELINE FACTORS

AUTHORS:

Dr Muhammad Shahan Raza, Dr Saadia Rafique, Dr Momena Zia

ABSTRACT:

Objective: The aim of this study is to examine the spectrum of reasons of chronic cough in our region and to find out the correlation of various reasons of chronic cough and different baseline factors as body mass index, age and gender and comparison with other populations. Methodology: A sum of 236 patients who visited Mayo Hospital, Lahore from March 2018 to March 2020 were the participants of this transverse research work. We defined the chronic cough as cough from more than 8 weeks. Most common reasons of chronic cough were variant asthma, ILD (Interstitial Lung Disease), allergic rhinitis, Gastroesophageal reflux complication, BHR (Bronchial Hyper Reactivity), cough induced by ACE-inhibitor and some others. We also recorded the clinical as well as demographic data. Results: Average age of the patients was 45.160 ± 16.50 years. The average body mass index of the patients was 26.230 ± 4.680kg/m2. Major reason of chronic cough was variant asthma in in 47.0% (n: 111) patients. There was a positive correlation of the age of the patients with the Interstitial Lung Disease and cough induced by ACE-inhibitor. There was high presence of Interstitial Lung Disease & ACE-inhibitor induced cough in female patients. There was a significant association of BMI with the ACE-inhibitor induced cough. Conclusion: Variations of epidemiology of chronic cough, variant asthma, allergic rhinitis & ACE-inhibitor cough is comparable to data present in the world whereas there is existence of the differences with the epidemiology of Interstitial Lung Disease. There is requirement of further research works in this particular field to define the local trends and to compare these trends with other populations. KEYWORDS: Demographic, Interstitial Lung Disease, ACE-I Induced Cough, Chronic, Baseline, Bronchial Hyper Reactivity, Asthma.