Dr Saira Abbas, Dr Khansa Majid, Dr Muhammad Abdur Rehman
Objective: Hypertension is very serious risk factor for the development of cardio-vascular and heart diseases in Sialkot, Pakistan. The evaluation of the effectiveness and safety of the anti-hypertension medication in different private hospitals is much significant. Significance arises due to the high incidence of hypertension in the multi-cultural region. This research work assessed the usage of Anti-hypertension medications among the patients present with hypertension alone or with some other clinical condition. Methodology: This research work carried out on four hundred hypertension patients who were recruited randomly from different private hospitals of Sialkot to assess the effectiveness and safety of the anti-hypertension medication in this region. Diagnosis of hypertension alone or in combination with other clinical condition carried out in the patients. Patients from both genders were the participants of this research work. This research work included the patients from all the classes of society. The collection of the data carried out from the medical files of the patients, conducting interviewing with doctors, nurses or by taking interviews of patients in the duration of this research work. Results: The findings of this research work showed that most of the patients were males (87.50%). There was association of some factors with hypertension as profession, age and gender. 82 % patients of hypertension were present with the history of hypertension in their family. We found no significant difference in diastolic BP between patients of both genders (average DBP; 79.0 Vs 82.90 mmHg correspondingly, P = 0.0760), but we found a significant difference in average SBP between both genders (average SBP 149.0 Vs 138.0 mmHg correspondingly, P= 0.0440). The stated adverse reactions of the medications in this research work breathe shortness, headache, edema, dizziness, vomiting, and problems of gastro-intestinal tract and cramps of muscle. Conclusion: There are many factors which are accountable for the contribution of the rise in Blood Pressure; most important risk factors are the life style and history of the complication in family. Combination treatment has association with very high rate of occurrence of adverse reactions of drugs; enough to permit either reducing the amount of medications or change in the prescribed medication. There is requirement of more efforts from the patients and professionals to reduce the danger of uncontrolled hypertension in our region. KEYWORDS: Hypertension, Myocardial Infarction, Professionals, Medication, Adverse, Drugs, Complications.