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EFFECTIVENESS OF PROPHYLACTIC VENOUS MANAGEMENT OF ONDANSETRON FOR ANTICIPATION OF BACKBONE ANESTHESIA ENCOURAGED HYPOTENSION IN AGED RESPONDENTS

Dr Maryam Haroon

Objective: Hypotension remains maximum known side consequence related through backbone anesthesia. Numerous models were verified to discover passable defensive quantity. Foremost goal of the current research remains to discover efficiency of prophylactic management of inj. ondansetron for anticipation of backbone anesthesia encouraged hypotension in ageing cases. Study design: Double blind, randomized measured test. Place and duration of study: The existing research remained led in Sir Ganga Ram Hospital Lahore from 02 March 2016 to September 2017. Methodology: Overall 110 respondents remained designated for our research experiencing non-possibility sample procedure, also separated into 2 sets of 55 apiece experiencing accidental statistics table. Individually respondent stayed preloaded through ringer’s lactate explanation in the dosage of 11 ml/kg. Respondents of Set A conventional 9 mg of ondansetron 4 to 5 min previous to management of backbone anesthesia; while respondents of Set B remained vaccinated standard saline 4. Information remained composed also investigated experiencing SPSS version 21. Chi square trial remained experienced to associate hypotension among 2 sets. The p-value < 0.06 remained occupied as substantial. Results: Average age of Set A remained 65.17 ± 9.48 years, while that of Set B remained 63.59 ± 9.98 (p value= 0.40). Average mass of Set A remained 73.65 ± 6.83 kg, while that of Set B remained 71.67 ± 6.97 kg (p - value= 0.296). Hypotension remained existing in 24 (48%) respondents in Set A, wherever as this remained existing in 35 (70%) cases in Set B (p value= 0.027). Bradycardia remained noted in 4(07%) against 12(23%) cases in Set A also B individually (p=0.022). Conclusion: Researchers accomplish that venous management of 9 mg of ondansetron, 6 min preceding to subarachnoid chunk, remains real in reducing occurrence of hypotension also bradycardia in ageing cases. Key words: Ondansetron; Spinal anesthesia; Hypotension.

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