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THE CONSEQUENCE OF VENOUS DEXAMETHASONE ON POST-OPERATIVELY AGONY, VOMITING ALSO NAUSEA AFTERWARDS INTRATHECAL PETHIDINE ALSO BUPIVACAINE IN INFERIOR APPENDAGE ORTHOPEDIC OPERATION

Dr. Hammad-Ur-Rahman, Dr. Awais Asghar, Dr. Ahsan Latif.

Background: Intrathecal pethidine offers outstanding post-operatively analgesia nevertheless remains related through substantial vomiting, nausea in addition additional side effects. Current research remained completed to assess effectiveness of venous dexamethasone to improve post-operatively analgesia also to decrease their side effects. Methodology: In the current prospectively, randomized, dual blind, placebo measured research was led at Services Hospital Lahore from May 2017 to April 2018, where overall 90 cases of ASA mark 1 also 2, experiencing elective inferior appendage orthopedic operation underneath sub-arachnoid chunk remained randomized into 2 sets. Set C (n=45) established 3 ml brackish also Set D (n=45) established 0.2 mg/kg dexamethasone intravenously as the bolus beforehand intrathecal anesthesia. In altogether cases vertebral anesthesia remained managed through 16 mg bupivacaine also 16 mg pethidine. Afterward operation, cases remained enquired to notch its discomfort at 3, 5, 7, 13, 19 also 23 hours through VAS score. The occurrence of post-operatively vomiting nausea, pruritus also breathing despair remained noted also associated amongst 2 sets. Results: The discomfort score on VAS at 7, 13, 19, 23 hrz subsequently to operation, average sum of release analgesic dosages in 1 day also incidence of PONV remained meaningfully inferior (p<0.06) in dexamethasone set (Set D). Conclusion: Management of intravenous dexamethasone (0.2 mg/kg) unbiassed beforehand subarachnoid chunk remains san actual manner of attractive post-operatively analgesia through intrathecal pethidine also this decreases occurrence of PONV. Key Words: Meperidine; Dexamethasone; PONV; VAP Scale; Adjuvants, Anesthesia; Valuation, Discomfort.

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