ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

EFFECTIVENESS OF TIOTROPIUM AMONG CHILDREN SUFFERING FROM ASTHMA

Dr Muhammad Salman Akhtar, Dr Sajjad Ahmad, Dr Anab Baloch

Objective: The aim of this research work is to study the effectiveness of Tiotropium among children suffering from asthma. Methodology: In this research, there were eighty children who were the victim of asthma. We prescribed the Fluticasone Propionate Aerosol or the Fluticasone Propionate Aerosol in addition with Tiotropium to these children randomly for the duration of 12 weeks. Results: There was a considerable better effect on the function of lungs in both of the groups during different intervals of week in comparison to the optimum level. Furthermore, as compared to healthy control group having significant level of P value less than 0.050, in Tiotropium group lungs function also improved. Yet there was no particular dissimilarity in the occurrence of chronic asthma between these groups (36.30% & 26.80% respectively; p>0.050). In the Tiotropium group, we had minimized the usage of SABAs (short acting beta2-adrenoceptor agonist) and quantity of days. It also reduced the awakenings during the night. In both study groups there were no any harmful effects. Conclusion: By using Tiotropium the function of lungs improves notably, reduction in the utilization of SABAs and awakening also decreases in children suffering from asthma. Still, it has some unpleasant effects. Key Words: Peak Expiratory Flow, Tiotropium, Forced Vital Capacity, Effectiveness, Awakenings, Asthma

FULL TEXT