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CONCENTRATION OF TOTAL ANTI-OXIDANT STATUS AMONG FEMALES SUFFERING FROM BREAST CANCER

Dr Wajahat Rashid, Dr Shabina Ahmad, Dr Hamna Saleem

Objective: The aim of this research work is to calculate the concentration of TAS (Total Anti-Oxidant Status) among females suffering from cancer of breasts. Methodology: This research work is case-control study carried out in Jinnah Hospital Lahore. Total 20 females suffering from the complication of breast cancer and 20 healthy controls with matched age were the part of this research work. We measured the TAS of serum in both groups. Results: The average TAS in the group of patients 0.91 ± 0.32 mmol/l was much lower in comparison with the participants of the control group 1.82 ± .14 mmol/l. Conclusion: The recent research work showed that females suffering from breast cancer have very low level of total anti-oxidant status in comparison with the healthy control females. It is the matter of great concern that oxidative harm may happen in those patients who deplete the anti-oxidant defense of their body causing a very low level of total anti-oxidant status. The management of the supplements of anti-oxidants status like a blend of Vitamin-A, Vitamin-C & Vitamin-E are essential in the females with high risk of the development of breast cancer or after operation or with anti-cancer medicines. KEY WORDS: Anti-Oxidative, Cancer, Pathophysiology, Serum, Neoplasm, Tissues & Immune, Concentration.

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