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A DESCRIPTIVE RESEARCH TO ASSESS OCCURRENCE OF HYPONATREMIA INDUCED BY TERLIPRESSIN AMONG ACUTE VARICEAL BLEEDING PATIENTS

Dr. Ayesha Ejaz, Dr. Umair Atta, Dr. Aisha Naveed

Objective: The objective of this research was to assess hyponatremia induced Terlipressin among acute variceal bleeding patients. Materials & Methods: This descriptive research was conducted at Mayo Hospital, Lahore from July 2017 to March 2018 on a total of one hundred patients who were presented with acute variceal bleeding. All the patients were Hyponatremia induced Terlipressin were also examined. All the patients faced the onset of acute variceal bleeding because of portal hypertension who were in the age bracket of (20 – 60) years from both genders. We did not include all those patients who presented hepatocellular carcinoma, hyponatremia, hypothyroidism, nephritic syndrome, Addison disease, severe diarrhoea, renal failure, cardiovascular disease, levels of serum sodium (≤ 135 mEq/L), hypersensitive patients, pregnant patients and unwilling patients. Results: The patients were enrolled in the age bracket of (20 – 60) years and the mean age of these patients was (45.78 ± 8.43) years. In the total one hundred patients, there were 37 patients of terlipressin induced hyponatremia. Majority of the patients were in the age group of (20 – 40) years and among these patients 17 presented Terlipressin induced Hyponatremia (37.78%). Another major age group was (41 – 60) years was observed in 55 patients; whereas, 20 presented Terlipressin induced Hyponatremia (36.37%). Conclusion: The outcomes of this research reflect a higher occurrence of Terlipressin induced hyponatremia. No correlation was observed between age, gender and Terlipressin induced hyponatremia. Key Words: Sodium Levels, Vasoactive Drugs, Upper GI Bleeding, Terlipressin and Hyponatremia.

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