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ASSOCIATION OF VENOUS BOLUS QUANTITIES OF PHENYLEPHRINE AND EPHEDRINE TO CURE HYPOTENSION AFTERWARDS SPINAL ANESTHESIA

Abdur Rehman, Dr Khalid Hussain, Dr. Manzara Mudassar

Background: Hypotension succeeding spinal anesthesia (SA) for cesarean distribution might got significant results for parturient also can disturb newborn baby result. Purpose: The main purpose of our current research remained to associate venous bolus quantities of phenylephrine also ephedrine to cure hypotension afterwards spinal anesthesia for cesarean unit also consequence of vasopressors on dangerous consequence in rapports of Apgar score. Methodology: The overall 210 parturient satisfying enclosure measures remained randomly owed into 2 sets of hundred and five apiece. Our current research was led at Lahore General Hospital, Lahore Pakistan from February 2017 to January 2018. Lumbar perforation remained completed in inactive location also 20 mg, 0.6% hyperbaric bupivacaine remained assumed intra-ethically to each respondent. Altogether cases remained positioned prostrate through 18-degree leftward adjacent slope location. Whether hypotension happened afterwards spinal anesthesia (SBP fewer than 95 mm Hg or else decline in SBP extra than 25% of starting point either remains inferior) remained cured through whichever 110μg phenylephrine in Set-A or else 7 mg ephedrine in Set-B boluses assumed intravenously. Results: Solitary venous bolus dosage of phenylephrine 110 μg remained actual in cure hypotension in 93% parturient whereas ephedrine 7mg endured actual in 79% parturient, that remained mathematically substantial (p= 0.0008). Here remained not any variance in average Apgar scores (p = 0.78) at 2 minutes also (p = 0.08) at 7 minutes among 2 sets. Frequency of bradycardia (HR < 52 beats/minutes.) remained suggestively developed in Set-A as associated to Set-B (p=0.039). Conclusion: Intravenous bolus quantity of phenylephrine 110 μg also ephedrine 7mg remained mutually real in curing hypotension afterwards spinal anesthesia for elective cesarean piece. Average Apgar scores of new born baby at 2 also 6 minutes remained similar amongst 2 sets. Key Words: SA, cesarean unit, hypotension, ephedrine also phenylephrine.

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