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ANALYSIS OF EFFICACY OF RECTAL INDOMETHACIN IN PREVENTION OF PANCREATITIS PATIENTS

Dr Umar Hammad Rashid, Dr Zarmeena Zulfiqar, Dr Aalia Rubab

Introduction: Acute pancreatitis is the most common complication of endoscopic retrograde cholangio-pancreatography (ERCP). Objectives of the study: The basic objective of the study is to analyze the efficacy of rectal indomethacin in prevention of pancreatitis patients. Material and methods: This cross sectional study was conducted in THQ Hospital, Pindi Bhattian during November 2018 to march 2019. The data was collected from 50 patients of acute pancreatitis. Patients already had raised amylase or acute pancreatitis, history of chronic pancreatitis or had a contraindication to NSAIDs were excluded from the study. Results: The data was collected from 50 patients. The mean age was 35.23±2.50 years. Age distribution of the patients was done, it shows that 30% in Indomethacin and 29.33% without Indomethacin group were between 15-50 years of age while 70% in Indomethacin and 70.67% without Indomethacin group were between 51-85 years of age, mean+SD was calculated as 56.28+8.39 and 55.72+7.84 years in both groups respectively. Gender distribution shows that 55.33% in Indomethacin and 53.33% in those without Indomethacin group were male while 44.67% in Indomethacin and 46.67% in those without Indomethacin group were females. Conclusion: It is concluded that the rectal indomethacin significantly decreased PEP risk among high- or average-risk population undergoing ERCP and provided strong evidence for current guidelines in clinical practice.

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