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ANALYSIS OF POTENTIAL RISK FACTORS FOR BREAST CANCER IN PAKISTANI WOMEN

Dr Shehroz Rana, Dr Shahid Iqbal, Dr Sundus Bukhari

Introduction: Cancer is a leading cause of mortality and morbidity worldwide, counting for 7 million deaths per year. It is the second most common cause of death in developing countries. Objectives of the study: The main objective of the study is to analyse the potential risk factors for breast cancer in Pakistani women. Material and methods: This cross sectional study was conducted in Health department of Punjab during November 2018 to March 2019. The data was collected from 50 female breast cancer patients. The main eligibility requirements for this study included the patient's written informed consent, metastatic breast cancer, patients entering first-line chemotherapy (chosen by clinicians) with or without targeted therapy, life expectancy of at least three months, and measurable or evaluable disease. Results: The results indicates that CTC, CEA and ALP are the best indicating serum biomarkers for the diagnosis and progression of breast cancer. Mean, median and SD shows that there is a significant relationship in these serum biomarkers. CTC and serum marker values at inclusion repartition in percentile, mean, median range are given in Table 01. ConclusionIt is concluded that CTC and ALP are the important biomarkers for the analysis of progression of breast cancer in females.

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