ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

IMPACT OF STATINS ON OUTCOME OF PATIENTS SUFFERING FROM CEREBRAL ISCHEMIC STROKE

AUTHORS:

Dr Toheed Rehman, Dr Khalid Hassan, Dr Wahid Gul

ABSTRACT:

Objective: CIS (Cerebral Ischemic Stroke) is very frequent in the population with elder age. The use of Statins appears to be very effective in the reduction of the disability resulted by cerebral ischemic stroke. The aim of this research work is to determine the impact of Statins on the outcome of cerebral ischemic stroke. Methodology: All the patients of cerebral ischemic stroke who got admission in the Mardan Medical Complex, diagnosed with the clinical & para-clinical results in the year of 2018 were the participants of this research work. The patients were those persons who were using Statins at least three months before the cerebral ischemic stroke and controls never used Statins in their life. The measurement of the motor activity carried out on the basis of MRS (Modified Rankin Scale). The modified Rankin scale was comparing the variable at admission & discharge time from this very hospital. If there is no alteration in the motor condition or it becomes worse, it defined the adverse outcome. Results: Total 230 patients of cerebral ischemic stroke in which one hundred and three were females were the part of this case work. The average age of the patients was 71.59 years. The amount of the patients of CIS with scores of MRS lower than 4 was much high in the group of Statins in comparison with the controls at the discharge & admission time. The proportion of the patients with adverse outcome was very low in the group of Statin in comparison with the group of controls. We found the same results when the adjustment of the both groups carried out for hypercholesterolemia. Conclusion: Outcome in the patients who were using Statins prior to cerebral ischemic stroke was much better in comparison with the persons who were not taking Statins. It appears sensible to advocate Statins to decrease motor disability & resulting good outcome in the patients present with high danger of acquiring cerebral ischemic stroke. KEY WORDS: Neurological, Statins, Cerebral Infarction, Hypercholesterolemia, Central Nervous System, Disability.

FULL TEXT

Top
  • Follows us on
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.