ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

NARCOTIC EFFICACY OF BUPIVACAINE 0.5% WITH LIGNOCAINE 2% IN ADDITION TO ADRENALINE IN EPIDURAL ANESTHESIA BY UTILIZING BIS SCREEN

Dr Irfan Shahzad, Dr Waseem Riaz, Dr Asif Saif Ullha Khan.

Objectives: This examination was led to look at the narcotic efficacy of bupivacaine 0.5% with lignocaine 2% in addition to adrenaline in epidural anaesthesia by utilizing BIS screen. Study Design: A double and randomized-blind study. Place and Duration of study: Visually impaired investigation was led in Services hospital, Lahore from January 2018 to January 2019. Methodology: Sixty patients, ASA physical status I or II, of age group 20 – 65 years, experiencing elective gynaecological medical procedure under epidural anaesthesia, were arbitrarily yet similarly put into two groups (group B and group L). Patients got (2ml/portion) bupivacaine 0.5% or lignocaine 2% with adrenaline in group B and group L individually, to accomplish a tangible square up to T8 level. After affirmation of tangible bar, propofol mixture was begun at a rate of 100 µg/kg/min to get a BIS estimation of ≤ 80 and the time was estimated (beginning time). The medical procedure was permitted to begin following the beginning time. Propofol imbuement was titrated to keep up the BIS esteem at 60 – 80. Imbuement was ceased toward the finish of the medical procedure. The time taken to achieve the BIS of ≥90 was recorded as 'recuperation time'. The measure of propofol devoured for the beginning of sedation and aggregate sum expended amid the medical procedure were noted and analyzed. Result: There was no significant contrast with respect to statistic information and beginning time in the two groups (P > 0.05). Recuperation time was significantly delayed in group B than group L (5.57 ± 1.25) min and (4.38 ± 0.94) min individually (P < 0.05). A portion of propofol expended for the beginning of sedation was significantly low in group B than group L, (17.13 ± 4.22) mg versus (27.77 ± 8.39) mg separately (P < 0.05). The aggregate sum of propofol expended was additionally significantly low in group B than group L, (140.33 ± 34.59) versus (184.80 ± 38.21) separately (P < 0.05). Conclusion: We presume that epidural square with 0.5% bupivacaine is related with less propofol utilization when contrasted with 2% lignocaine with adrenaline with keep up BIS 60 – 80 and thus is progressively successful. Key Words: Bupivacaine, BIS, Lignocaine with adrenaline, Onset Time, Propofol and Recovery Time.

FULL TEXT