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TITLE:

RATE OF OCCURRENCE AND RISK FACTORS OF HCV AMONG FEMALES HAVING PREGNANCY

AUTHORS:

Dr Ommyya Usman, Dr Shaher Bano Fatima, Dr Haris Afzal

ABSTRACT:

Objective: The aim of this research work is to find out the rate of occurrence & risk factors of HCV (hepatitis C virus) among females having pregnancy at Nishtar Hospital Multan. Methodology: This was an elaborate transverse research work conducted in the OPD of Gynecology department in Nishtar Hospital Multan from June 2018 to November 2018. A sum of total four hundred pregnant females from 16 to 45 year of age, who visited OPD for checkup were the part of this research work. The already identified patients of hepatitis C were not the part of this research work. Elaborate past history including age of the patient, parity number, factors of risk as history of blood transfusion, past history of surgeries, deliveries through vagina collected and we performed the relevant investigation, Patients on normal routine examination if discovered to be anti-hepatitis C virus positive on Immuno-Chromatography Test or ICT (ICT) procedure, their further confirmation carried out with method of ELISA. The collection of the information carried out on a well-organized Performa. Results: In the duration of this research work, four hundred females in the department of gynecology underwent testing for hepatitis C, among total 6.60% (n; 27) were present as positive for antibodies of hepatitis C virus. The range of the included females was from 16 to 45 years. Total 7.90% (n: 13) females with pregnancy having hepatitis C virus positive antibodies were in the age group of 26 to 30 years of age. Out of twenty-seven positive hepatitis C virus patients, 70.30% (n: 19) were multi-gravida and 29.60% (n: 8) pregnant females were prim-gravida. Most of the females (77.0%) found with the past infections history. Conclusion: There is very remarkable occurrence of infection of HCV among females having pregnancy in our setting. The most probable prompting factors were transfusion of blood, surgery & injection. Keywords: Multi-Gravida, Hepatitis C, Pregnancy, Liver Cirrhosis, Hepatocellular Carcinoma, Mortality, Antibodies, ELISA.

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