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TITLE:

THE INCIDENCE OF CO-MORBIDITIES RELATED TO OBESITY: A SYSTEMATIC REVIEW STUDY

AUTHORS:

Dr. Ammad Javaid Chaudhary, Dr. Saad Javaid, Dr. Shanzay Amin

ABSTRACT:

Background: Obesity can increase the risk of a number of medical conditions which can lead to further morbidity and mortality. The purpose of this study is to find out the incidence of each co-morbidity related to obesity and overweight. Methods: A literature search for the twenty co-morbidities identified in a preliminary search was conducted in Medline and Embase. Studies added that met our inclusion certain (prospective cohort studies of sufficient size reporting risk estimate based on the incidence of disease) were extracted. Results: total 89 studies were identified. Only 18 comorbidities which met the inclusion criteria were found. This review found statistically significant associations for obesity with the incidence of type II diabetes, all cancers except esophageal (female), pancreatic and prostate cancer, all cardiovascular diseases (except congestive heart failure), asthma, gallbladder disease, osteoarthritis and chronic back pain. The strongest association between overweight defined by body mass index (BMI) and the incidence of type II diabetes in females were noticed. Statistically significant associations with obesity were found with the incidence of type II diabetes, all cancers except esophageal and prostate cancer, all cardiovascular diseases, asthma, gallbladder disease, osteoarthritis and chronic back pain. Conclusion: Both overweight and obesity are associated with the incidence of multiple comorbidities including type II diabetes, cancer and cardiovascular diseases. Key words: obesity, comorbidity, overweight diseases.

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