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MALE INFERTILITY AND EJACULATE ENZYMES

Afrim Zeqiraj, Zafer Gashi, Shkelzen Elezaj, Zehra Hajrulai-Musliu, Hesat Aliu, Sadi Bexheti, Nexhbedin Beadini , Sheqibe Beadini, Agim Shabani*

Infertility is defined as without the ability of a sexually active mate to reach a pregnancy despite regular and unprotected sexual intercourse for more than 12 months. Of all couples trying to have children, 17% -25% will be diagnosed as infertile, where about 50% of these cases are attributed to male infertility. Materials and methods: The statistical processing of the data is done with the statistical package SPSS 22.0. From the statistical parameters are calculated the arithmetic average, the standard deviation, the minimum and the maximum value. Qualitative data testing was done with the X2-test of quantitative data that had normal T-test distribution, while those with non-normal distribution with the Mann-Whitney test or Kruskal Wallis test. The difference is significant if P <0.05. Results: The study included 257 males of different age groups, of whom 169 were in the study group and 88 in the control group. In the study group were men with asthenospermia, oligospermia and oligoasthenospermia, whereas in the control group were men with normospermia. With the distribution of the surveyed by age group and X2-test groups we have distinguished significant statistical significance (X2 = 10.28, P = 0.006). In the study group compared to that less control was under the age of 30 and older aged 40+ years. Conclusions: It is recommended that such an analysis of DNA fragmentation determination in the sperm becomes part of the clinical trials of Andrology laboratories. The creatine kinase activity evaluation in the seminal plasma constitutes a useful biochemical marker in determining the potential for male fertility. Key words: Creatine kinase, Sperm DNA fragmentation, Halotech/Halosperm.

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