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TITLE:

A STUDY OF THE OUTCOME OF ASPHYXIATED NEWBORNS AT NISHTAR HOSPITAL MULTAN

AUTHORS:

Muhammad Numan, Umaima Malik, Jam Ali Haider

ABSTRACT:

Objective: The study was conducted with the objective of determining the outcome of newborns diagnosed with birth asphyxia. Methods: This cross-sectional retrospective hospital-based study was conducted at Nishtar Hospital Multan from August to December 2019. Total 50 patients with birth asphyxia were included with gestational age ≥ 37 weeks with Apgar score ≤ 6 at 5 minutes. Babies with congenital defects, evidence of infection and maternal drug addiction were excluded from the study. All babies were resuscitated according to the guidelines of American Heart Association. Data were then tabulated and analyzed. Results: Out of total 50, there were 10 (20%) cases of severe birth asphyxia (Apgar score: 1-3) and 40 (80%) cases of moderate birth asphyxia (Apgar score: 4-6). Staging of hypoxic ischaemic encephalopathy (HIE) was performed according to Sarnat’s staging. Thirty percent of these cases presented with various stages of HIE and the incidence was higher in low Apgar score group. The common presentations of HIE cases had depressed neonatal reflexes, seizures, lethargy, and pupillary abnormalities. The common acid base disturbance was metabolic acidosis which was observed only in babies with HIE-3. Two neonates (4%) died during the hospital stay due to multiorgan failure and severe metabolic acidosis. Conclusion: The mortality rate increases with the severity of birth asphyxia which can be predicted by the APGAR score. Keywords: Birth asphyxia, Hypoxic ischaemic encephalopathy, Apgar score

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