::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

ANALYSIS OF MATERNAL AND PERINATAL OUTCOME IN PRETERM LABOR

AUTHORS:

Dr Javeria Ashfaq, Dr Faiqa Falak, Dr Arooj Fatima

ABSTRACT:

Introduction: Spontaneous preterm birth (PTB), defined by the World Health Organization as birth before 37 completed weeks of gestation, is one of the main causes of perinatal death in the developed countries. Objectives of the study: The main objective of the study is to analyze the maternal and perinatal outcome in preterm labor. Material and methods: This cross sectional study was conducted in SIMS, Lahore during June 2019 to December 2019. Sample size was calculated with WHO sample size calculator using following figures: CI 95%, Power of study 80% proportion of outcome variable (p1) 21%. Patients with multiple gestation, obstetric bleeding, fetal anomaly, allergic reactions, intrauterine death and patients who refused to participate in the study were excluded. Results: A total of 72 female patients were included in the study. Mean age and gestational age of the patients was 25.36±3.8 years and 32.09±1.78 weeks. 56.9% (n=41) patients had 15-25 years of age and 43.1% (n=31) patients fell in age group 26-40 years. Gestational age distribution showed that majority of the patients i.e. 58.3 (n=42) had gestational age 29-32 weeks and 41.7% (n=30) had 33-36 weeks of gestational age. Conclusion: It is concluded that nifedipine is a better tocolytic agent than nitroglycerin for the preterm patients, when used for pregnancy prolongation.