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TITLE:

RELATIONSHIP BETWEEN MID-LIFE AND END-OF-LIFE BLOOD PRESSURE PATTERNS AND INCIDENT DEMENTIA

AUTHORS:

Dr Aiman Nawal, Dr Komal Zaheer, Dr Saba Islam

ABSTRACT:

Importance: The relationship between end-of-life pulse and discernment may be based on the proximity and chronicity of past hypertension. Decreased circulatory pressure at the end of life as a result of delayed hypertension may be related to poor subjective outcomes. Objective: To investigate the relationship between conceptions of mid-life and end-of-life BP with subsequent dementia, mild subjective impairment and psychological decline. Method: Our current research was conducted at LGH Lahore from January 2019 to December 2019. The following section examines existing hypotheses about the pathogenesis of AIDS and designates symptomatic and remedial ways of treating the disorder itself. Results: Among 4769 members (2825 [60%] women; 984 [24%] black; visit 5 mean age [SD], 78 years; visit 1 mean age run, 45-67 years; visit 5 mean age go, 67-93 years), there were 519 (13%) cases of dementia between visits 5 and 6. The rate of dementia for limbs with normotension in their 40s (n = 835) and at end of life was 2.32 (96% CI, 1.01-2.73 per 100 man-years); for normotension in their 40s and hypertension at end of life (n = 1564), 1.98 (96% CI, 1.71-2.33 per 100 man-years); for hypertension in their 40s and at end of life (n = 1035), 2. 84 (96% CI, 2.41-3.36 per 100 man-years); for midlife normotension and end-of-life hypotension (n = 940), 2.08 (96% CI, 1.69-2.55 per 100 man-years); and for midlife hypertension and end-of-life hypotension (n = 394), 5.27 (96% CI, 4.41-5.34 per 100 man-years). Conclusion: In this network based on the accomplice with long-term development, continuous hypertension in mid- and end-of-life and an example of contrasting mid- and end-of-life hypertension and hypotension, and regular BP in mid- and end-of-life, were associated with increased risk of dementia. Key words: Mid-Life And End-Of-Life Blood Pressure, incident dementia.

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