Dr Muhammad Ali Shah, Dr Sidra Azhar, Dr Naima Khan
Aim: To evaluate the effect of injection syntocinon in comparison with injection syntometry in reducing the risk of postpartum hemorrhage and to observe side effects after using two drugs. Study design: A case control study. Setting and duration: In the Obstetrics and Gynecology department of Nishter Hospital Multan for one year duration from February 2019 to February 2020. Methodology: Three hundred patients were selected based on convenient sampling with no probability. This study was conducted on patients admitted to the delivery room with a single pregnancy, in whom vaginal delivery was close, patients were divided into three categories. Group I consisted of 150 patients who received only syntocinone in the form of a 5 unit I / V injection. Group II consisted of 150 patients who received a 5 unit syntocinon injection and a 0.5 mg ergometrine injection. I / M injection was given after a placental explosion. Blood loss during labor was estimated by measuring the number of blood clots and weighing towels and cotton balls soaked before, and postpartum delayed hemorrhage was noted within the first 24 hours after delivery. Maternal blood pressure was measured immediately after delivery. Side effects such as nausea, vomiting and headaches have been reported 1 to 2 hours after delivery. Results: The rate of 46.7% blood loss 500 ml in the syntocinone group was observed to be significantly high compared to the tbe frequency of 36.7% syntometine in PC 0.05, the rate of adverse effects in group I syntocinon was 8% and 17.3% in group group II syntometry. The data revealed a significantly high rate (Z = 2.39 p = 0.008) of adverse effects in the group of patients with syntometin and then in the group with syntocinon at PC 0.05. Conclusion: oxytocin alone is as effective as using syntometry to prevent postpartum hemorrhage, but is associated with significantly less maternal side effects. KEYWORDS: Syntocinon, Syntometrine, Postpartum Harmorrhage, Prevention, Delivery.