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TITLE:

INCIDENCE OF IRON DEFICIENCY ANEMIA IN FIRST DEGREE RELATIVES OF PATIENTS WITH BETA THALASSEMIA MAJOR

AUTHORS:

Dr. Asma Nazir, Dr. Shaista Akbar, Dr. Amna Arif

ABSTRACT:

Objective: To find out frequency of iron deficiency anemia in first degree relatives beta thalassemia major patients. Study Design: A comparative, non-invasive study. Place and Duration: In the Medicine and Hematology department of Sir Ganga Ram Hospital, Lahore for one year duration from February 2019 to January 2020. Methods: A total of 300 people were included. Out of which 200 subjects were first degree relatives of beta thalassemia major patients and 100 were normal control subjects. Complete blood count with peripheral smear was done. Serum iron, serum TIBC, serum ferritin, hemoglobin electrophoresis and HbA2 estimation were carried out. Results: There were 93 men and 107 women with thalassemia, aged 18-50. Normal or increased serum ferritin levels were found in 186 people, and low serum ferritin levels (iron deficiency anemia) were found in 14 people in the range <10 ng / ml. Conclusion: The percentage of patients with iron deficiency anemia in relatives of patients with major beta thalassemia is 7%. Key words: Iron deficiency anemia, first degree relatives, high beta thalassemia

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