Dr Muhammad Waqar Rehan, Dr Miraa Qutab, Dr Faisal Nadeem Khan, Abdul Basit
Background and objective: Non‐alcoholic liver disease (NAFLD) is the common form of chronic Liver disease (CLD), and is abundantly increasing worldwide. The main objective of the study is to analyses the severity of metabolic syndrome in patients suffering from nonalcoholic fatty liver disease. Material and methods: This cross-sectional study was conducted in Shalimar Medical and Dental College Lahore, Pakistan during January 2019 to July 2019. The data was collected through non-probability sampling technique. The data was collected from 100 liver cirrhosis patients. The age range for this study was 20 to 60 years. Blood sample was collected for the serum analysis of liver enzymes. Results: In this study the data was collected from 100 patients with biopsy-proven NAFLD, a relationship between the severity of the metabolic syndrome and NAFLD was observed. The mean age of the patients were 45.67±3.56 years. The levels of ALT in patients was 258.2±91.73, 79.66±28.63, and 50.73± 8.4 respectively as compared to normal control (11±3.42). Aspartate aminotransferase levels were significantly raised in viral hepatitis, alcoholic liver disease and cirrhosis patients. Conclusion: It is concluded that high prevalence of NAFLD and elevated aminotransferases in obese adolescents with IR, and the implications for their health is concerning. The close associations between NAFLD and MetS support screening for other co-morbidities associated with MetS.