Dhakne Hemant and Phadke Shraddha
The main purpose of spray drying method in pharmaceutical technology is to get dried particles in desired characteristics like their physicochemical and morphological properties. In these recent studies, there is identifying the important of spray dryer technology compare to all other drying method used in food and pharmaceutical industry. In this review there is basic construction of spray dryer machine and their process and how the construction part of machine affects the characteristic of product (dried particles). The further year there is modification in spray dryer machine to improve a characterization of product as per required. Types of spray dryer are done based on direction air and feed flow, depend upon number of passes before the dried product is separated, based on aspect ratio, fluidize spray dryer, multistage spray dryer, compact spray dryer, integrated filter dryer, FILTERMAT® dryer. In this present review is focus on spray dryer has critical parameter which will be affect the properties of the final dried product, this parameter taken under consideration. Innovation in spray drying technology improve efficiency in food and pharmaceutical products. In this there are advantages of spray dryer technique compare to other drying method. Spray drying method is mainly used in encapsulation of drugs, co-processed excipients and drugs, improve the compatibility of various drugs, increasing the aqueous solubility and bioavailability of the active substances and taste masking microsphere in oral disintegrating tablets. Aim of the present review is to give all possible information and brief usefulness of spray dryer technology. Keywords: Spray dryer, atomizer, pharmaceutical, co-processed excipients, aqueous solubility, bioavailability, modified release, Inhalation powder.