::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

INCIDENCE OF ASYMPTOMATIC PERIPHERAL DISEASES IN METABOLIC SYNDROME AFFECTED PATIENTS

AUTHORS:

Dr Raana Shahid, Dr Tehrim Tahir, Dr Ayesha Ashraf

ABSTRACT:

Aim: To determine the frequency of asymptomatic peripheral arterial disease (PAD) in patients with metabolic syndrome. Study design: A descriptive case series study. Place and Duration: In the Medicine department of Sir Ganga Ram Hospital, Lahore for one-year duration from February 2019 to February 2020. Subjects: 110 patients with metabolic syndrome were selected for this study. The ankle-brachial index was calculated by measuring systolic blood pressure (using a Doppler probe) in the brachial arteries, posterior tibia and dorsal foot on both sides. The highest of the four ankle and foot measurements is divided by the highest of the two brachial measurements to reach ABI. The ankle-brachial cut-off value for diagnosing peripheral arterial disease was <0.90. Results: The mean age of patients was 51.6 ± 8.9 years. 63 (57.3%) patients were men and 47 (42.7%) were women. There were 79 (71.8%) patients with a history of diabetes and 66 (60%) patients with a history of hypertension. The patients' average ankle and shoulder index was 0.95 ± 0.046. There were 14 (12.7%) patients with an ankle brachial index> 0.90. The distribution of peripheral arterial disease was 14 patients (12.7%) and 96 (87.7%) without PAD. Conclusion: Metabolic syndrome is associated with an increased risk of vascular events in patients with peripheral arterial disease. Key words: metabolic syndrome, peripheral artery disease (PAD), ankle-brachial index (ABI)