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SAFETY AND EFFICACY OF AMNIOTIC MEMBRANE IMPLANT IN VENOUS LEG ULCERS

Dr Hafiza Alina Ilyas,Dr Alishba Anum,Dr Chaudhry Hamza Sarwar

The basic objective of the research is to evaluate the safety and effectiveness of amniotic membrane (AM) application in venous leg ulcers (VLU). In a specific design of non-controlled pre-post clinical trial, a specialized AM fragment was subjected to the ulcer in rigorous sterility conditions. Principal result strategies: the rate of total healing, ulcer is reduction percentage and diurnal and nocturnal pain assessment. Control visits: at primary and 1, 2, 3, 4 and 8 weeks immediately after treatment. Ten patients were employed (79.6 years). Three weeks after AM implant, pain had entirely vanished and ulcer area had lowered to just about halved and, 2 months immediately after AM implant, ulcer area was lower in significantly more than 80% along with two thirds of individuals the ulcer had been completely recovered. No significant adverse reactions were noticed. The current research produces emerging information reinforcing the concept that AM dressing is a safety and reliable alternative to heal VLU Keywords: Venous leg ulcers; Amniotic membrane; Ulcer healing; Pain; Effectiveness; Safety

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