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TITLE:

A CROSS SECTIONAL STUDY TO EVALUATE IF CHLORHEXIDINE MORE EFFECTIVE THAN POVIDINE IODINE IN CONTROLLING SURGICAL SITE INFECTIONS

AUTHORS:

Dr Qarib Mukhtar, Dr Alishba Rahim, Dr Amna Rafique

ABSTRACT:

Objective: Chlorhexidine (CHG) has been used extensively as a topical antiseptic agent, having broad clinical use in interventional medicine and procedures. clinical studies have rendered chlorhexidine gluconate to be a superior perioperative skin-prepping agent. The following research will be focusing on suggesting that CHG has a broad and safe range of applications when used in interventional procedures for reducing the risk of postoperative surgical site infections (SSI). Methodology: A cross sectional study was carried out in sheikh Zayed hospital Rahim Yar Khan consisting of 250 surgical patients undergoing clean and clean contaminated surgeries ,sample size calculated with WHO sample size calculator, half of them were scrubbed with 2% chlorhexidine gluconate and 70% isopropyl alcohol and remaining half scrubbed and painted with an aqueous solution of 10% povidone-iodine.patients were followed from perioperative time till 1 month after surgery for any local and systemic signs of infection at the site of operation.the study ranged over a period of 3 months consisting of a local examination of the wound for and pus/serosanguinous foul smelling discharge,redness,tenderness ,pain or fever associated with malaise, loss of appetite and chills. Results: The rate of surgical site infection was significantly lower in the chorhexidine-alcohol group than in the povidone-iodine group (9.5% vs 16.1%; p value 0.004; relative risk, 0.59; 95% CI, 0.41 to 0.85). Chlorhexidinealcohol was significantly more protective than povidoneiodine against both infections. Conclusions: Preoperative cleansing of the patient’s skin with chlorhexidine-alcohol is more beneficial to cleansing with povidone-iodine for preventing surgical site infections.

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