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AN OBSERVATIONAL STUDY ON THE PERIPHERAL BLOOD MONOCYTES IN MULTIPLE SCLEROSIS

Dr. Muhammad Kaleem Ullah Khan, Dr. Daud, Dr. Muhammad Shafiq

Objectives: we know that we are surrounded by germs in our environment and it harmful effects on use to protect our body from these germs we need strong immune system Monocytes (MO), macrophages, and microglia has a type of leukocyte which protected our central nervous system inflammation which cause by multiple sclerosis (MS). The objective of our research study was to assess quantity of infinite MO count and %age in incidental blood of MS patients during the attacks. Methodology: In this study we determine the %age of MO by test the blood specimen of MS patients, we studied twenty those patients who suffered from acute cerebrovascular disease (CVD) & twenty those patients who was healthy. Results: The mean measure of total MO tallies in multiple sclerosis patients were 606. 670±, acute cerebrovascular disease was 746. 520±414.760 and control groups were 360.00±109. The average values of Monocytes %age in multiple sclerosis patients were 8.34 ± 2.61%, acute cerebrovascular disease were 5.56 ± 2.48 percent and control group were 5.360±1.500 percent. The average %age of Monocyte was automatically high in multiple sclerosis patients with respect to both groups of CVD and control (P greater than 0.001). Conclusion: Our research outcomes recommend a conceivable amount of an expansion in MO actuation in the intense intensifications of Multiple Sclerosis. Key Words: Fringe Blood, Monocytes, Multiple Sclerosis, Exacerbation, Conceivable.

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