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TITLE:

INCIDENCE OF MALNUTRITION INFLAMMATION COMPLEX SYNDROME IN END STAGE RENAL DISEASE PATIENTS ON MAINTENANCE DIALYSIS

AUTHORS:

Dr. Maria Mubarak, Dr. Muhammad Mubasher Nadeem, Dr. Muhammad Salman Khan

ABSTRACT:

Objective: To determine the incidence of Malnutrition Inflammation Complex Syndrome related to malnutrition (MICS) in patients with end-stage renal disease maintained on hemodialysis. Study Design: A cross-sectional study. Place and Duration: In the Nephrology Department of Services Hospital Lahore for one year duration from June 2017 to June 2018. Methods: In the study, total of 62 patients were selected. All end-stage renal disease patients on maintenance hemodialysis (twice in a week for more than 3 months) were included and patients with chronic infections, chronic liver disease and ARF were not included in the study. To evaluate the Malnutrition Inflammation Complex Syndrome associated with malnutrition, malnutrition inflammation score (MIS) was used. For categorical and continuous variables for percentages or proportions, standard deviation and mean were calculated. To determine the MICS ratio in patients receiving hemodialysis treatment, Chi-square test was used. Results: 46 years ± 12.59 SD (18-72 years) was the mean age. 34 (55%) were female and 28 (45%) were male. Hemodialysis time was 1 year and 28 (45%) in 26 (42%) patients. The prevalence of complex malnutrition syndrome (MICS) was observed in 60 (97%) patients with mild MICS and in 29 (47%) patients with moderate MICS. MICS syndrome was more common in the 31-40 age group (12% in mild MCIS and 14% in mild MCIS). In females, MICS was higher and in male patients mild. Conclusion: It is supposed that many of the end-stage renal disease patients maintained on hemodialysis treatment (97%) had evidence of (MICS)Malnutrition Inflammation Complex Syndrome. Key Words: Hemodialysis, Malnutrition Inflammation Complex Syndrome, MIS.

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