::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

THE RELATIONSHIP OF STEATOSIS WITH THE GRADING OF HISTOPATHOLOGY & LIVER BIOPSIES STAGING IN THE PATIENTS OF HEPATITIS C

AUTHORS:

Dr Assma Majeed, Dr Ayesha Akram, Afshan Riaz

ABSTRACT:

Objective: The purpose of this research work is to conclude the relationship of steatosis with the grading of histopathology & staging the biopsies of the liver in the patients of the hepatitis C. Methodology: This study was probable research work study grounded on the biopsies of the liver of the patients suffering with hepatitis C. The examination of the stained slides of H & E carried out to find out the activity of histology, score of fibrosis & steatosis. Results: There was a degree of steatosis present in twenty eight patients out of fifty patients. Fourteen patients revealed with no steatosis out of twenty two patients found with the activity of Grade-1. Twelve patients out of thirteen patients with greater steatosis grades had showed the high steatosis grades of score of serious NS (necroinflammatory score). The P value of less than 0.0050 considered as significant. Conclusion: The vital cofactor in the enhancement of in the activity of NS & fibrosis of the patients of patients of hepatitis is steatosis. Steatosis may be an identifier of NI & an identifier of the progression of the fibrosis. KEY WORDS: NI, biopsy, liver, steatosis, identifier, activity, vital, stage, hepatitis.