::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

CODEN : IAJPBB
issn 2349-7750

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TITLE:

OSTEOMYELITIS IN THE CHILDREN SUFFERING FROM SICKLE CELL ANEMIA IN ALLIED HOSPITAL FAISALABAD

AUTHORS:

Dr Muhammad Aftab Younas, Dr Muhammad Zeeshan, Dr Muhammad Usman Arif

ABSTRACT:

Objective: The most common cause of morbidity & mortality among the patients of sickle cell anemia is osteomyelitis. The main objective of this research work was to find out the frequency and design of this complication among the children suffering from the disease of sickle cell anemia Allied Hospital Faisalabad. Methodology: This study was a retroactive analysis of every available data of the patients of sickle cell anemia having less than 16 year of age. These patients admitted in the children ward of Allied Hospital Faisalabad from the January 2014 to December 2018. Patients found with incomplete records were not the part of this research work. Results: Review of the records of 187 patients of sickle cell anemia carried out. The average age of the population of this case study was 6.950 ± 4.230. Females were less in number as compared to the males. Among 187 patients suffering from SCA, 15 patients found with osteomyelitis. The occurrence of osteomyelitis was 0.08%. We found the AO (acute osteomyelitis) as accounted for hundred percent patients. The most common organism which separated from the blood of 5 was Klebsiella pneumonia. High temperature, swelling the legs & pain in bones were the most common mode of appearance. Most frequently involved bone was Tibia found in 8 patients. The organisms which were the main cause of the disease were very sensitive to gentamycin & ceftazidine in 55.0% cultures of the blood samples. Conclusion: The major presence of the Klebsiella pneumonia shows that there is a clear alteration in the accepted design of this complication in which the specie of the Salmonella were the main organisms as a cause of this disease previously. KEY WORDS: Anemia, Temperature, Pneumonia, Hyposplenism, Neutrophil, Infected Limb.