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TITLE:

REVEALING COMPARISON OF THE MEDICINE MISOPROSTOL AND DINOPROSTONE USED IN INDUCED PREGNANCY

AUTHORS:

Dr. Hadiqa Jafri, Dr. Nadia Afzal, Dr. Ayesha Nadeem

ABSTRACT:

Objective: We aimed in this analysis to differentiate the suspected fetal compromise in 6 hourlies vaginally administered 3 doses of misoprostol as compared to dinoprostone which is used for induced pregnancy. Study Design: This analysis is comparatively observational type. Place and duration: This analysis was performed for the duration of one year from March, 2018 to February, 2019 at Gynae Ward Mayo Hospital Lahore. Methodology: A total number 200 female cases suffering from induced pregnancy of 41 weeks were chosen for this analysis which were casually separated equally with number of 100 cases in dinoprostone group and misoprostol group. In the rotation of 6 hours dosage of misoprostol was 50 mcg every time with the upper limit of 150 mcg as a total of 3 medications and dinoprostone was used only 2 mg per 2 medications. Fetal heart beat was constantly supervised after induction. Symptoms of fetal compromise as meconium staining of liquor of membrane and CTG were recorded. Apgar score at 5 minutes was recorded after the birth of baby if any requirement to take the baby to nursery or artificial respiration is vital. Results: In misoprostol group and dinoprostone group the average of cases was 25.4 ± 4.5 years and 23.3 ± 3.4 years respectively and the average period of induced delivery rotation in misoprostol and dinoprostone group was 16.4 ± 6.4 and 13.1 ± 4.6 hours respectively. Number of 40 cases were delivered with LSCS and 60 cases were delivered through spontaneous vaginal delivery with the percentage of 40.0% and 60.0% respectively in the misoprostol group while number of 36 cases were delivered with LSCS and 64 cases were delivered through spontaneous vaginal delivery with the percentage of 64.0% and 34.0% respectively. In misoprostol group and dinoprostone group the mean Apgar value at 5 minutes was 8.5 ± 0.9 and 8.6 ± 0.9 respectively. In the Misoprostol group and dinoprostone group number of 5 and 2 cases with the percentage of 5.0% and 2.0% respectively were admitted in ICU. Conclusion:As a comparison of dinoprostone, misoprostol was used for the induced pregnancy at 50 mcg medication without reduction of its affect related to Delivery and induction and the suspected fetal compromise haven’t raised was obtained through this analysis. Key Words:Misoprostol, dinoprostone,Fetal distress, induced pregnancy,

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