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TITLE:

A BRIEF REVIEW ON ROLE OF NANOCARRIER AS ANTIHYPERTNESIVE AGENTS

AUTHORS:

KIRAN KULKARNI, SACHIN LOKAPURE, AMRUTA TIDAKE

ABSTRACT:

Now days Hypertension or high blood pressure is a common chronic heart disease. It is associated with various symptoms like amnesia, improper speech, blindness, peripheral artery disease, brain stroke, heart attack etc. it mainly involves the role of autonomous nervous system, cardiac output and renin-angiotensin aldosterone system. The present study mainly deals with the application of nanotechnology and nanoparticulate drug delivery systems in the formulation of various antihypertensive drugs for the treatment of hypertension. Applications of various nanoparticulate drug delivery systems like solid lipid nanoparticles, polymeric nanoparticles, nanosuspensions and self-nanoemulsifying drug delivery systems for antihypertensive drugs have been reviewed which indicate that these nano carriers can improved the bioavailability of various poorly soluble and permeable antihypertensive drugs. Key Words: Hypertension, Nano carrier, Nano emulsion.

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