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ACUTE AND CHRONIC TYPHOID FEVER: A COMPARATIVE ANALYSIS BETWEEN ADULTS AND CHILDREN PATIENTS OF HYDERABAD REGION, SINDH, PAKISTAN

Munazza Sharif Farooqui, Tayba Khan, Aisha Zafar Ali

Among the most common infections in developing is the Typhoid fever which occurs as a result of poor hygienic conditions at multiple levels in food and water management process. It is caused by bacteria known as Salmonella Typhi diagnosed by widal test, typhidot test and blood culture with different sensitivity and specificity levels. This work was conducted in year 2012 in 4 different hospital labs at Hyderabad City of Sindh Province of Pakistan. Typhoid positive cases in males and females and children and adults were separated and similarly the –ve cases too and then compared using chi-square at 0.05 significance level. There were total 285 patients evaluated for typhoid fever out of which 131cases were positive while 154 cases were negative. There were 122 males and 163 females while there 121 acute and 10 chronic cases. Significant difference was seen between two genders with P-value0.00002 and similarly the difference was also significant for acute and chronic cases between children and adults p-value 0.00001. Conclusion: significant difference was observed between males and females, children and adults and acute and chronic cases. Key Words: Acute Typhoid, Chronic infection, Typhi dot, Salmonella Typhi