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Shehwar Nadeem, Ambreen Tauseef, Munaza Javed, Mehwish Qamar, Syeda Abeer Fatima, Saadia Sajjad


Background: Presence of thyroid disorders in general population and in patients with diabetes mellitus is inconsistent in various populations. Thyroid disorder and diabetes in postmenopausal females may have certain specific adaptation. The thyroid profile might have a link between thyroid and diabetic postmenopausal women of different weight categories. This particular study was designed to compare thyroid stimulating Hormone (TSH), Total thyroxine (TT4), total triiodothyronine (TT3), free thyroxine (FT4) and Free triiodothyronine (FT3) in diabetic and non-diabetic postmenopausal and non-diabetic premenopausal females. Objectives: To Compare thyroid profile in postmenopausal diabetic and non-diabetic subjects with premenopausal non-diabetic subjects. Methods: A total of 78 female subjects were divided into four groups; postmenopausal diabetics and non-diabetics, having weight ≤ 59 kg and below and postmenopausal diabetics and non-diabetics with weight ≥ 60 kg respectively. Blood samples were analyzed by ELISA. Results: The lower level of FT3 was seen in the diabetic females of both the lower and higher weight categories but statistically more significantly found in higher weight group. In diabetic patients, TT3 was found to be statistically low in those who were above and below 60 kg of weight. Conclusion: Thyroid gland functions found to be adapted in postmenopausal diabetic females of different weight categories. Keywords; Thyroid profile, postmenopausal, diabetics

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