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TITLE:

ACCURACY OF BEDSIDE BLOOD GLUCOSE ESTIMATION BY GLUCOMETER USING CAPILLARY AND VENOUS BLOOD SAMPLES

AUTHORS:

Ahmad Shehzad, Ahmad Riaz, Muhammad Husnain, Ahmad Usman

ABSTRACT:

Objective: Determination of the difference and correlation between capillary and venous glucose monitoring by glucometer in comparison to venous glucose analysis by standard laboratory. Methods: The study was conducted on a non-probability convenient sample of 20 consenting patients visiting the emergency department of Nishtar Medical University, Multan. Their blood glucose levels were synchronously analyzed using a bedside On Call Plus glucometer on capillary and venous derived samples. The venous sample was also sent for comparative testing to the central hospital laboratory using Beckman Coulter AU680 Clinical Chemistry Analyzer. Student's t-test and Pearson's correlation analysis was done to determine the difference and correlation of results. Results: The mean age of 20 subjects was 47±5.7. The mean laboratory glucose, mean capillary blood glucometer glucose, and mean venous derived blood glucometer glucose was 127.47, 138.01 and 143.96 mg/dl, respectively. A statistically significant difference (10.45 mg/dl, p=0.001) between the mean values for the laboratory and capillary glucose samples was noted. The difference between the mean values for the laboratory and venous glucometer samples was also found statistically significant (16.39mg/dl, p=0.001). There was a 5.94 mg/dl (p=0.05) difference between the capillary and venous derived glucometer tested samples as well. Thus difference was observed between the glucometer and the laboratory blood glucose results. Conclusion: There is a significant yet small variation in the blood glucose results analyzed by laboratory and glucometer. The difference between capillary and venous glucometer measurement may be clinically small and irrelevant, but caution must be exercised in accepting the results as equivalent or using either as substitutes for the standard laboratory blood glucose results. Keywords: Glucometer, Capillary blood, Venous blood, Laboratory, Accuracy.

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