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TITLE:

RATE OF OCCURRENCE OF DYSLIPIDEMIA IN PATIENTS SUFFERING FROM LUPUS NEPHRITIS

AUTHORS:

Dr Maham Wajid, Dr Mawra Karim, Dr Hunain Faheem

ABSTRACT:

Objective: This research work aimed to find out the rate of occurrence of dyslipidemia in the patients suffering from LN (Lupus Nephritis) and its relationship with the proteinuria’s degrees. Methodology: This transverse research work included sixty five patients who completed the standard of American College of Rheumatology (ACR) for SLE and present with renal involvement, appearing in Mayo Hospital, Lahore from August to November 2019. After complete twelve hours of overnight fasting, we evaluated their samples of blood from TC (Total Cholesterol), TG (Triglycerides), HDL (High Density Lipoprotein and LDL (Low Density Lipoprotein). We noted the demographic variables and characteristics of their disease. We divided the patients into groups on the basis of proteinuria degree as having proteinuria greater than 1gm or equal or less than 1gm. We used the SPSS V.21 for analysis of data. We performed the correlation of the individual profiles of lipids with the proteinuria’s degree. Results: The most common abnormality of lipid discovered in this research work was hypertriglyceridemia (58.50%). TC & LDL-C was much high in 55.40% and 30.80% patients correspondingly. We found the low HDL in 21.50% patients. We also noticed the enhanced dyslipidemia’s frequency in those patients who were present with proteinuria of greater than 1gm (P < 0.050). Conclusion: We observed the dyslipidemia with high rate of occurrence in the patients suffering from LN and it has strong association with the proteinuria’s degree. KEY WORDS: Association, dyslipidemia, ACR, HDL, TC, TG, LDL, Lupus Nephritis, occurrence, SLE, correlation.

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