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TYPES AND FREQUENCY OF GESTATION TROPHOBLASTIC DISEASE

Dr Areeba Sanaullah, Dr Hamza Bhatti, Dr Muhammad Talha Bhatti

Objective: This research work was conducted to assess the types and rate of the GTD (Gestation Trophoblastic Disease) in endometrial & hysterectomy samples obtained for evaluation with the help of histopathology. Methodology: This research study carried out in pathology department of services Hospital, Lahore. Total 1342 patients suffering from EC (Endometrial Curettage) & examination of total 1832 samples carried out with the help of hysterectomy. The collection of the samples started in March, 2009 & last sample received in April 2018. The ethical committee of the hospital approved the conduction of research study. The examination of the H/E stained slides made of glass carried out. All the patients gave verbal consent to participate in this research work. SPSS v.15 was in use for the analysis of the collected results. Results: Out of total patients suffering from EC, two hundred and forty-two patients were available with hydatidiform mole, out of total two hundred and forty-two patients of hydatidiform mole, 69.350% (n: 172) patients were available with partial mole & 30.240% (n: 72) patients were available with complete mole; chorio-carcinoma was present in 5 patients while among 1832 samples of hysterectomy, we found only 9 patients with invasive mole. The occurrence of chorio-carcinoma is not same at every place and provided at 1100000 & 170000 pregnancies in the countries of the West and 1250 & 16000 pregnancies in the continent of Asia. Conclusion: The most common GTD diseases was hydatidiform mole in accordance with the findings of this research work. Key Words: Endometrial, Mole, Suffering, Pathology, Conduction, Hysterectomy, Placental.

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