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TITLE:

ANALYSIS OF SALIVARY PROFILE IN TYPE 2 DIABETES MELLITUS ADULT PATIENTS

AUTHORS:

Dr Ahmad Hassan, Dr Haseeb ur Rehman, Dr Ramna Chahal

ABSTRACT:

Introduction: Diabetes mellitus is a chronic condition with severe long-term, disabling complications, and unknown remedy that is characterized by disorders in carbohydrate, fat, and protein metabolism. Aims and objectives: The basic aim of the study is to analyze the salivary profile in type 2 diabetes mellitus adult patients. Material and methods: This case control study was conducted in Holy Family Hospital, Rawalpindi during April 2018 to November 2018. The data was collected from 100 type-2 DM patients. We divided the data into two groups. One was control group and one was diseased group. The enrolled cases had a history of T2DM which had a minimum duration of 2 years. Samples were centrifuged at 5000 rpm, the supernatants were collected and they were stored at – 8000C until further analysis. Results: The data were collected from 100 patients. The mean age of the participants in the study was 46.5 years. No significant differences were observed between the sexes in both groups in pH, salivary flow rates and biochemical parameters. Salivary pH was observed to be significantly lower in diabetics as compared to that to non-diabetics. Flow rate was significantly diminished in diabetics. Biochemical determinations showed significant differences between non– diabetics and diabetics. Conclusion: It is concluded that there is a significant variations in both physical and biochemical parameters of saliva in T2DM, thereby emphasizing the fact that the salivary composition was not just a reflection of the oral health state of a subject, but also of one’s systemic state.

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