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ANALYSIS OF DIFFERENT FETOMATERNAL OUTCOME IN JAUNDICE COMPLICATING PREGNANCY IN LAHORE

Dr Ayesha Shafaq, Dr. Shahjahan Anwar, Dr Momina Masud

Introduction: Jaundice refers to yellow appearance of skin, sclera and mucous membranes resulting from increased bilirubin concentrations in body fluids. It is usually detectable clinically when plasma bilirubin exceeds 3 mg/dl. Aims and objectives: The basic aim of the study is to find the fetomaternal outcome in jaundice complicating pregnancy in Lahore. Material and methods: This cross sectional study was conducted in Mayo Hospital, Lahore during March 2018 to November 2018. The data was collected from 50 pregnant female patients who were suffering from jaundice and visited the OPD of the hospital regularly. All the patients were assessed thoroughly by both clinical examination and investigations in the form of complete blood count, liver function. Viral markers for hepatitis such as IgM HAV antibody, HBV (HBsAg, HBeAg, anti-HBe), HCV (anti-HCV antibody), HEV antibody (IgM) were done in all patients. The data was analyzed using SPSS version 19.0. Results: The data was collected from 50 pregnant females who were suffering from jaundice. . The data suggest clearly that CD4 count decreases in abnormal liver function. There were non-significant relationship present in diseased group treated with different therapies like interferon and glutathione as as p<0.05. Maternal mortality was 4.76% due tojaundice.Among 2 deaths one patient died due to leptospirosis infection and one died due to HELLP syndrome and DIC. Two cases serum bilirubin was around 11 mg/dl. Conclusion: It is concluded that viral hepatitis is the most common cause of jaundice in pregnancy. The factors responsible for high maternal mortality in our country were poor nutrition, prevalence of anemia, delay in seeking medical advice and delay in referral to the hospital.

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