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TITLE:

ANALYSIS OF CHILDHOOD KIDNEY DISEASE AND RISK OF RENAL PROBLEMS IN PAKISTANI POPULATION

AUTHORS:

Muhammad Aftab Saleem, Najam ul Hassan, Asia Zafar

ABSTRACT:

Introduction: Chronic kidney disease (CKD) is a major public health problem, and preventing CKD and/or delaying progression of CKD patients to end-stage renal disease (ESRD) is a major task for the nephrology community. Aim and objectives: The basic aim of the study is to analyse the childhood kidney disease and risk of renal problems in Pakistani population. Methodology of the study: This cross sectional study was conducted in Health Department Punjab during April 2018 to November 2018. The data was collected from 100 patients who were suffering from kidney diseases. The age range for this purpose was 1 to 10 years. For this purpose we make two groups of study. One group was control group and the other group was suffering from kidney problems. Then we collect the socio economic status and therapy status. Then we analyze the data and find that either statin therapy is helpful for patients or not. Results: The data was collected from 100 patients with mean age range 5.65±6.78 years. The inappropriate activation of this system causes hypertension, fluid retention, and inflammatory, thrombotic, and atherogenic effects that may contribute to end-organ damage in the long term. Table 01 shows the values of analysis of statin therapy in patients. It shows the comparison between two groups on the basis of functional values. Conclusion: It is concluded that mild kidney abnormalities or injury in childhood may confer a risk of ESRD in adulthood, even when there is no overt compromise of renal function in adolescence.

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