ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

ANALYSIS OF ANTI-INFLAMMATORY EFFECT BETWEEN INTRCAMERAL TRIAMCINOLONE ACETONIDE AND TOPICAL DEXAMETHASONE AFTER PHACOEMULSIFICATION

Dr Maria Javaid, Dr Anam Manzoor, Dr Anum Shah

Introduction: Phacoemulsification is the most frequently employed method of cataract extraction. Although the phacoemulsification technique has improved greatly over the years, still it involves surgical trauma which predisposes the individual to post-operative inflammation. Aims and objectives: The basic aim of the study is to analyze the anti-inflammatory effect between intrcameral triamcinolone acetonide and topical dexamethasone after phacoemulsification. Material and methods: This comparative study was conducted in Foundation University Medical College, Islamabad during March 2018 to November 2018. The data was collected from 60 patients who undergo phacoemulsification. The data was divided into two parts, one group were given single intracameral injection of triamcinolone acetonide 1mg at the end of surgery using a 27-guage cannula. Group B get post-operatively Dexamethasone 0.1% eye drops (one drop every four hours) and Moxifloxacin 0.5% eye drops (one drop every six hours) were given for 4 weeks with gradual tapering of dose of dexamethasone eye drops. Results: The data was collected from 60 patients, divided into two groups. The mean age of the selected patients was 55.55 ± 5.68 years. The two groups were comparable with respect to age and sex. There were no significant differences between the groups in age or sex (P > 0.05). Injection of TA into the anterior chamber resulted in a ‘snow-globe effect’ of various densities at slit-lamp examination. Despite the suspension of crystals, it was easy to assess cell and flare between crystals. Conclusion: It is concluded that single dose intracameral injection of triamcinolone acetonide and postoperative topical dexamethasone are equally effective in controlling post-operative inflammation after phacoemulsification.

FULL TEXT