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AWHICH IS EFFECTIVE FOR THE PURGATION OF UMBILICAL CORD TO PREVENT OMPHALITIS? A RANDOMIZED CLINICAL TRIAL TO COMPARE METHYLATED SPIRIT AND 4% CHLORHEXIDINE

Dr. Qasim Mahmood Ghouri, Dr Ayesha Zahoor, Dr Sumble Shager

Background: A number of antiseptics are being utilized for umbilical cleansing which includes, methylated spirit, alcohol, iodine, silver sulphadiazine, chlorhexidine, triple dye, eosin, acriflavine and gentian violet, current antibiotic application, and human milk. Objectives: To make a comparison between the effectiveness of 4% chlorhexidine and methylated spirit in the purgation of the umbilical cord for preventing omphalitis. Method: This random clinical trial was carried out at Jinnah Hospital, Lahore (September 2017 to March 2018). A total of 96 healthy full-term infants of both genders weighing equivalent and over to 2.50Kg delivered through vagina were included in the study. Patients with the need of antibiotics were excluded from the study. Chlorhexidine group and Methylated spirit were named as group 1 and group 2 respectively. The researcher inspected the umbilicus by his own for omphalitis signs. Result: In this study, the Gestational age range was 36 to 43 weeks with an average gestational age of (39 ± 1.10) week. In this research study, omphalitis prevention or normal umbilicus shedding within one week of start of therapy(efficacy) was observed in 45 (93.80%) patients within group 1, 4% chlorhexidine and in 38 (80%) patients within methylated spirit (Group 2) with value p 0.038 which is statistically very significant. Conclusion: This study affirmed that the efficacy of four percent chlorhexidine is more as in comparison to methylated spirit to prevent omphalitis. Keywords: Omphalitis, Chlorhexidine and Methylated Spirit.

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