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TITLE:

A CRITICAL EVALUATION ON IDENTIFICATION OF RISK FACTORS OF DIABETIC KETOACIDOSIS AND ITS EFFECT ON PATIENTS

AUTHORS:

Dr Sidra Hanif, Dr Muhammad Awais, Dr. Qasim Mahmood Ghouri

ABSTRACT:

Background: Diabetic ketoacidosis (DKA) is life threating which affects people with diabetes. It needs early diagnosis and proper management. For the sake of preventive measures, risk factor must be known. Objective: This study aimed at identification of risk factors of diabetic ketoacidosis and its effect on patients. Design of study: It was a case-control study. Duration: Study was done from Feb, 2017 to Jan, 2018. Patients and Methods: This study was done in medicine department of LGH, Lahore. 100 patients above 13 years of age suffering from diabetes were selected. 50 patients were enrolled as cases having KDA. Age and sex matched control was selected for each case. 50 patients in control group were diabetics. Primary end point was noted. Patients died during word stay or in emergency room. Alive patients discharged. SPSS version 21 was used for statistical analysis of data. Results: Maximum diabetic ketoacidosis was observed in 4th decade in patients. 10% patients of DKA died while 90% were discharged alive. 50% cases showed infections, poor following of medication on the part of patients (44%), new diagnosis (16%). These percentages are far greater than that of control group stroke, myocardial infarction, acute pancreatitis, dehydration and trauma were identified as major risk factors. Conclusion: Newly diagnosed diabetes, infections and improper following of medication increases risk for diabetic ketoacidosis. Keywords: Diabetic Ketoacidosis, Diabetes Mellitus, Risk factors.

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::INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES::

TITLE:

A RESEARCH STUDY TO ASSESS THE ONLAY AND SUBLAY TECHNIQUE TO REPAIR VENTRAL HERNIA

AUTHORS:

M Haris Baloch, M Hamza Khawaja, M Salman Baig

ABSTRACT:

Objective: The objective of this research was to compare sublay and onlay technique for the repair of ventral hernia in terms of postoperative drain removal time and wound infection. Methods: This randomized controlled study was held from June 2017 to March 2018 at Mayo Hospital, Lahore. The hernia patients were divided into two equal groups A and B. Group A was subjected to onlay technique while the latter was given sublay repair technique. After 1 year of index surgery operative repair was performed. This time period was necessary for scar maturation. After the experiment, data were analyzed using SPSS and time taken for drain removal of both the groups was compared. Results: There were 100 patients, half in each group. Mean age of patients present in group A was 40.30±0.23 days. The condition in terms of wound infection was also important. Conclusion: For repairing ventral hernia, sublay hernia repair was a good alternative to onlay repair of ventral hernia. Keywords: Ventral Hernia, Sublay, Onlay.

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