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A RESEARCH STUDY TO ANALYZE THE DIFFERENCE BETWEEN EFFICACY OF TIGECYCLINE AND METHIONINE HINDERED BY STAPHYLOCOCCUS AUREUS

Dr Nusair Ahmad, Dr Aamir Sajjad, Dr. Noor-ul-Falah

Abstract: Objective: The main purpose of the study was to analyze the differences between the effectiveness of tigecycline and methionine hindrance by Staphylococcus aureus. Material and Methods: The research was completed at Mayo Hospital, Lahore from November 2017 to August 2018. About 100 patients of the following disorder were studied. The identification of the disease was determined by 30 microgram disc of cefoxitin. This identification method was guided by Clinical laboratory Standard Institute diffusion method. Food and Drug Administration give the idea to use Kirby Bauer disk diffusion method to determine the receptiveness of the isolates to tigecycline. E Strip of tigecycline was used to decrease the inhibitory amount of the separates. Elucidation of the data was done by using FDA guidelines. Results: By disc diffusion technique all MRSA separates were susceptible to tigecycline. All the MRSA separates lies in the receptive range as determined by MICs of tigecycline. Conclusion: Tigecycline has been noticed to contain better effectiveness in opposition to MRSA separates. This was recorded in the era of mounting antibiotic opposition. Keywords: Antimicrobial Activity, MRSA, Tigecycline.

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