ResearcherID - CLICK HERE Scientific Journal Impact Factor (SJIF-2020) - CLICK HERE

TITLE:

IMPACTS OF HIGH LEVELS OF SERUM LEPTIN ON THROMBOCYTE ACCUMULATION IN KIDNEY PATIENTS

AUTHORS:

Dr Nayab Nasim Rana, Dr Shaista Naseem, Dr Anam Ilyas

ABSTRACT:

Abstract: Objective: The level of serum leptin was very high in the patients suffering from kidney diseases in accordance with normal healthy population. The aim of this study is to interrogate the impacts of the levels of serum leptin on thrombocyte accumulation in the patients under dialysis. Methodology: Total 43 patients under peritoneal dialysis were the part of this research work. The calculation of the thrombocyte accumulation carried out from complete blood, consequently the investigation of the impacts of various concentrations of recombinant leptin in human on the TA (Thrombocyte Aggregations) carried out. There was the utilization of 4 test cells. There was no addition of the leptin in the 1st test cell, rising leptin amount was increasing in 2nd, 3rd and 4rth cells to obtain the concentrations of 25 ng/ml, 50 ng/ml & 100 ng/ml correspondingly. Results: There was inhibition TA in recombinant leptin in the patients under dialysis. The average amounts of TA were very high in the 1st test cell when compared with the groups of leptin in the patients under peritoneal dialysis. We were unable to find out the significant disparity for average values of TA among every group. Conclusion: Future research works with high amount of the patients under peritoneal dialysis are the requirement to give the evidence of leptin on TA. Keywords: Membrane, Recombinant, Leptin, Serum, Dialysis, Accumulation, Thrombocyte.

FULL TEXT

Top
  • Follows us on
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.