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COMPARISON OF CONGO RED STAINING KIT VERSUS UROCOLOR TEST TO DETECT PROTEINURIA IN PATIENTS OF PREECLAMPSIA

Dr Mashal Masud, Dr Sara Akram, Dr Walliullah

Abstract: Objective: To compare the Congo Red staining kit with the urocolor test to evaluate the proteinuria in patients with preeclampsia. Study Design: A Cross sectional Study. Place and duration: In the Obstetrics and Gynecology department of Divisional Headquarter Teaching Hospital, Mohtarma Benazir Bhutto Shaheed Medical College, Mirpur AJK and Red Crescent Medical and Dental College Teaching Hospital, Lahore for one year duration from Feb 2018 to January 2019. Methods: A prospective, cross-sectional study including preeclampsia-diagnosed pregnant women and prenatal women with preeclampsia diagnosed clinically. A single 24-hour urine sample was analyzed with Congo Red to determine the presence of proteinuria among all patients, the qualitative results of urine dipstick for proteinuria and the determination of protein in the 24-hour collected urine is regarded as the gold standard. Differences between nominal conditions were determined by Mann-Whitney U test. Results: A total of 50 puerperal and pregnant women were selected for the study. In the statistical comparison between 2 and 3, 2 and 4, 3 to 4, the positive Congo Red in the fields reached a significant variation (p 40.001) in relation to the average proteinuria values for each. In contrast, there was no difference in the number of positive crosses with the urocolor test. Conclusion: Congo red has a high selectivity for beta folded proteins in preeclampsia and is a promising high-value test for the clinician. Key Words: Congo red, proteinuria, urocolor test, pregnancy.

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