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RATE OF METABOLIC ANOMALIES IN PATIENTS WITH URINARY STONE DISEASE

Dr Muhammad Junaid Shoukat, Dr Waseem Akram, Dr Muhammad Aqib Javid

Abstract: Objective: The objective of this research is to find out the rate of occurrence of metabolic anomalies in the urine of the patients suffering from the disease of urinary stones. Methodology: Total 200 patients having calculi in their urinary tract discovered with the help of ultrasonography & urography were the part of this research work. The collection of twenty-four-hour samples of urine carried out from every patient and delivered for PH value, uric acid, present of different elements as magnesium, calcium, oxalate & specific gravity. The samples of blood of every patient delivered for levels of serum in urea, uric acid, calcium & phosphate. Results: The average age of the patients was 38.0 ± 7.75 years. The most common complaint was pain of lumber & 82.50% patients were available to have the stones of calcium oxalate on their analysis chemically. We discovered the metabolic abnormalities in 90.50% patients, while there were no metabolic abnormalities in 9.50% (n: 19). Total 21.50% (n: 40) found with only one anomaly of metabolism & 78.50% (n: 157) found with different complications of metabolism. The very frequent observed anomaly of metabolism was hyperoxaluria available in 64.50% patients. Other important anomalies of metabolism were hypercalciuria, hypocitraturia, hypercalcemia & hyperuricemia. Conclusion: The results of this work concluded that rate of the metabolic anomalies was very high among the patients suffering from the calculi in their urinary tract. We also concluded some metabolic anomalies in this research work. KEY WORDS: Calculi, Urinary Tract, Hypercalcemia, Abnormalities, Anomaly, Phosphate, Hypocitraturia, Metabolism.

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