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OSTEOPOROSIS IN PEPTIC ULCER DISEASE

Luqman Qaiser, Muhammad Asim Iqbal, Muneeba Zafar

Abstract: Objective. To determine the frequency of osteoporosis in cases with peptic ulcer disease. Methods; It was a descriptive, cross sectional study that was conducted at Sir Ganga Ram Hospital Lahore, Sharif Medical City Lahore and DHQ hospital, Gujranwala from May 2018 to December 2018. The cases presenting with history of epigastric pain with age range of 20 to 60 years of both gender were considered. These cases then underwent upper GI endoscopy and finally the 100 cases of peptic ulcer were considered. The detailed data was collected. The cases with previous history of bone trauma, metabolic disorders, end stage renal or liver disease and those with diabetes mellitus were excluded. The cases with diagnosed PUD then underwent DEXA scan and score less than 2.5 was labeled with osteoporosis. Results; In this study there were total 100 cases out of which 56 were males and 44 females. The mean age was 35.44±5.35 years. Osteoporosis was seen in 10 (10%) of cases. Osteoporosis was more seen in females affecting 7 and 3 males out of their respective groups (p= 0.12). It was also more common in cases with age group more than 40 years where 8 cases were seen with p value of 0.04. There was no significant difference in terms of duration of PUD with osteoporosis (p= 0.78). Conclusion: Osteoporosis is not uncommon in cases of peptic ulcer disease. Higher age is significantly associated with this. Keywords: PUD, Osteoporosis, DEXA scan, T score.

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