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TITLE:

ASSESSMENT OF DENTAL PULP CHANGES OBSERVED AFTER LONG TERM USE OF CORTICOSTEROID DRUGS

AUTHORS:

Dr Abdul Samad Tayyab, Dr Muhammad Jameel Khan, Dr Umme-i-Hani

ABSTRACT:

Abstract: Introduction: It has been found that prolonged treatment with hormone leads to disorders affecting the electrolyte balance in the body, the dental literature contains a number of reports in which effects of cortisone on dental pulp have been studied. Objectives of the study: The main objective of this study is to assess the dental pulp changes observed after long term use of corticosteroid drugs. Material and methods: The cross sectional study was conducted in THQ Hospital, Haveli Lakhan during March 2018 to October 2018. The data was collected from 100 patients who can use corticosteroid drugs from the long time. The study groups were divided into two groups for the collection of data. One group was considered to be as the normal group and control group and the second one was the group of patients who received corticosteroid drugs during the treatment of dental pulp. The data was collected from both the groups for further analysis. Histopathology of these two groups were also done for further clarification. Results: The data was collected from 100 patients of both genders. Group I (no dexa-methasone) presented significantly higher values (p=0.01) than Group II (control) and Group III (dexa-methasone after cavity preparation), which means a significantly larger vascular area. Images from microscopic slides of specimens from Group II were closer in quality to those from Group III and presented a higher percentage of the area occupied by loose connective tissue. Conclusion: It is concluded that corticosteroids applied on the dentin proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels.

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